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49ers vs Cowboys: The Niners Are the Real Deal

WEEK 10 · SUN NOV 15 · 4:25 PM ET · FOX
SLATELINES PICKS 21+ · sportsbook links pay us a commission

Our edge: San Francisco is 7-1 and still went shopping at the deadline, and Dallas has won one of four at home. Our score: 49ers 31, Cowboys 23.

21+. SlateLines earns a commission from sportsbook links. Check availability in your state. Odds updated 11:47 AM ET.

COMPARE ODDSBest price highlighted · 11:47 AM ET
OUR PICKSFanDuelFanaticsBetMGM
49ers −7.5+172BEST+160+160
Brock PurdyPurdy O 17.5−114n/an/a

21+. Tap any price to bet it at that book. SlateLines earns a commission from sportsbook links.

01 · POINT SPREADOUR PICK

49ers −7.5

49ers −7.5: our chance it cashes49%51%49ers −7.5  +172FanDuel›Our estimate. Not a guarantee.

Half their third downs, every red-zone trip

The 49ers convert 51.7% of their third downs and have scored on every single trip inside the 20 this year. They average 29.4 points a game, and Brock Purdy has been sacked eight times all season. That’s an offense that stays on schedule and finishes drives, and it’s why this is their best start since 2019.

Christian McCaffrey has run for a touchdown in six straight games. And on Tuesday the 49ers sent a 2027 sixth-round pick to Indianapolis for Keenan Allen, who led the Colts with 40 catches, to patch up a banged-up receiver room. Rich get richer.

Points allowed per game
49ers19.5
Cowboys26.2
2026 season through Week 9 (ESPN team stats)

Jerry's house hasn't been much of a fortress

Dallas has won one of four home games: a 37-20 win over Washington in Week 2, then three straight home losses, the latest a 33-30 stunner against Arizona. The Cowboys give up 26.2 points a game, and coach Brian Schottenheimer said Monday that tight end Jake Ferguson and running back Tyler Goodson will both miss multiple weeks.

Dak Prescott can sling it with anybody, and Dallas scores 27.3 a game. But the 49ers allow 19.5, and Dallas can’t count on stops to keep pace.

CeeDee LambCeeDee LambDAL · WR

CeeDee Lamb over 7.5 receptions

With Ferguson out, Lamb is the whole passing game. He caught 10 of 16 targets for 195 yards against the Colts last week, and he had 17 catches in Houston in October. He’s seen double-digit targets in five of his last six games. If San Francisco gets out front like I think it will, Dak throws to 88 until his arm falls off. Lamb over 7.5 catches.

Moneyline: who winsSPREAD IS THE BETTER BUY

At −210 or worse you're paying a lot to skip points we think the Niners clear anyway. Lay seven and a half at plus money instead.

Best price: −215 at FanDuelFanDuel
How this blows up on me

Dak and CeeDee go off. Prescott has thrown for 335 yards twice in his last six games, and corners Deommodore Lenoir and Renardo Green were both day-to-day on Monday. If those two can't go, Lamb could go for 195 again and seven and a half is a lot to lay in a shootout.

Shop the number

The safe number is −4. Our score says Niners by eight, so we are laying seven and a half and getting +172 for it.

−7.5+172FanDuel
02 · PARLAYSSAME GAME

Parlays

MOST LIKELY2-Leg Same Game ParlaySGP
SF @ DAL · SUN 4:25 PM
49ers −7.5Alt spread+172
Purdy O17.5 rush ydsPlayer prop−114
EST. ODDS+411
Build this ticketFanDuel
OUR FAVORITE3-Leg Same Game ParlaySGP
SF @ DAL · SUN 4:25 PM
49ers −7.5Alt spread+172
Purdy O17.5 rush ydsPlayer prop−114
Lamb O7.5 recPlayer prop−106
EST. ODDS+892
Build this ticketFanDuel
CRAZY BET2-Leg Same Game ParlaySGP
SF @ DAL · SUN 4:25 PM
49ers Defense anytime TDPlayer prop+600
Kyle Juszczyk anytime TDPlayer prop+550
EST. ODDS+4450
Build this ticketFanDuel

The book sets the final price. Same-game legs are linked, so it is usually lower than these estimates.

03 · PLAYER PROPSOUR PICK

Purdy over 17.5 rushing yards

Brock PurdyBrock PurdySF · QBOver 17.5 in four of his last six games

Purdy has gone over this number in four of his last six games: 34 against Arizona, 29 against Denver, 28 against Washington and 40 with a touchdown against the Raiders last week. Dallas has 17 sacks, so Purdy will have to escape the pocket a few times. Two scrambles gets you there.

Brock Purdy: last 5 gamesLINE: O 17.5
29
6
28
5
40
DENWk 4 · 10 car✓ OVER
SEAWk 5 · 5 carUNDER
WSHWk 6 · 5 car✓ OVER
ATLWk 7 · 2 carUNDER
LVWk 9 · 7 car✓ OVER
Over 17.5 in 3 of the last 5 games.Purdy over 17.5 rushing yards  −114FanDuel›
Brock PurdyO 17.5 rush yds−114FanDuel
04 · LIVEIN-GAME

If this happens, tap that

Set before kickoff. Keep this open during the game. When one hits, tap it.

DON'T CHASEIf Purdy hasn't run for 10 yards by halftime, don't go buying his rushing number live. Let the ticket ride.

21+. One live bet per trigger. Live odds move fast, so check the price before you bet.

WHO YOU GOT?

Is San Francisco the best team in the NFC, or does Dallas expose them?

Tell me I'm wrong.

49ersCowboys

Go Niners. Faithful, let's ride.