College Football Tuesday Picks: October 27, 2026

Two Conference USA games on Tuesday night, and a Game Pick on both: Delaware at Western Kentucky, and Sam Houston at Missouri State.

These are Game Picks. Our college ratings haven’t beaten the lines in testing, so these are leans, and every one gets graded on the receipts page win or lose. We don’t post college player props.

Delaware at Western Kentucky, 7:00 PM ET, CBSSN

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Our PickWestern Kentucky Hilltoppers

Western Kentucky Hilltoppers -1.5

-110Fanatics

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Both teams are 3-4, and the ratings have them dead even, so home field decides it. WKU beat Missouri State 34-13 and Sam Houston 16-3. Hilltoppers at home in Bowling Green.

Sam Houston at Missouri State, 8:00 PM ET, ESPN2

Our PickSam Houston Bearkats

Sam Houston Bearkats +5.5

-108FanDuel

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Sam Houston is 1-6, but Missouri State is 2-5 and just gave up 61 to Delaware. The ratings make the Bears about a three-and-a-half-point favorite at home. Bearkats with the points.

Lines as posted Tuesday. Confirm them before kickoff.

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